is pentylene glycol the same as propylene glycol

There are many applications of propylene glycol: use of it as a feedstock for the production of polymers, as a component in some food items, as an anti-icing fluid, manufacture of electronic cigarettes, etc. I realized I am highly sensitive to PEG and PG and Polysorbate (and Heaven knows what else) a few months ago and eliminated all medications that have it as an ingredient.. not easy. Another immensely important advantage of pentylene glycol is that, in contrast to conventional alcohol, no dehydrating effect occurs even at a higher dosage. It is a colorless, odorless, slightly syrupy liquid that is a bit thicker than water. the not so good: It can irritate the eyes at high concentrations and when there is significant contact with the eyes. "Subchapter E - Animal Drugs, Feeds, and Related Products; 582.1666. Her reaction is different than most allergic reactions- her heart rate goes high. 4. Thats an amazing story and Im glad you found the cause of the problem. Description: Pentylene Glycol is a natural and environmentally sustainable direct replacement for the Petrochemical derived ingredient whilst also being Palm Free and PEG free. Propylene glycol is frequently used as a substitute for ethylene glycol in low toxicity, environmentally friendly automotive antifreeze. Dihydroxypropane. Dr. Belmeur advertised their product as Formulated without 9 additives (parabens, synthetic pigments, artificial fragrance, triethanolamine, mineral oil, benzophenone-3, animal-derived ingredients, propylene glycol, talc) or artificial fragrance. Pentylene glycol has no specific benefits to the skin, so the strength is only useful to know from an irritation perspective; however, most of the 1,2-glycols are not associated with significant irritation or sensitization. Even though Propylene Glycol is a good ingredient for skincare products, Propanediol is safer than Propylene Glycol. ", "Material Safety Data Sheet: Winter Care RV Antifreeze", "Association between electronic cigarette use and fragility fractures among US adults", "Toxicity Assessment of Refill Liquids for Electronic Cigarettes", "Predicting Abraham model solvent coefficients", "Atmosphere: Hazers, Fazers, Smoke and Fog 101 by Daniel Brea", "Outbreak of Lung Injury Associated with the Use of E-Cigarette, or Vaping, Products", Centers for Disease Control and Prevention, "Material Safety Data Sheet Propionaldehyde MSDS", "Database of Select Committee on GRAS Substances (SCOGS) Reviews", "Tests for the chronic toxicity of propylene glycol and triethylene glycol on monkeys and rats by vapor inhalation and oral administration", "Vaping vs Smoking: Is the Former Really a Healthier Alternative? Choose Propylene Glycol and Polyethylene Glycol-free products and enjoy healthier (and happier) skin. Propylene glycol is a colorless, nearly odorless, thick liquid. Propylene glycol is an organic compound having two alcohol functional groups in the same molecule. [52][53][54], Propylene glycol has not caused sensitization or carcinogenicity in laboratory animal studies, nor has it demonstrated genotoxic potential.[55][56]. Derived mainly from a petrochemical, Propylene Oxide from natural gas. July 4, 2022. 2 Hydroxypropyl. Wow, Thank You everyone for sharing your personal stories snd information. Propylene Glycol Free Balsam of Peru Free Oil Free Irritant Free Dye Free SLS Free Products That Don't Contain Pentylene Glycol Favorite Similar La Roche-Posay La Roche-Posay Toleriane Double Repair Face Moisturizer, SPF 30, 2.5 oz Favorite Similar CoTZ CoTZ Baby Non-Tinted Mineral Sunscreen, SPF40, 3.5 oz/100 g Favorite Similar Is Dipropylene equally as skin toxic? Pentylene Glycol has 5 carbons, 1,2-Hexandiol has 6 carbons and Caprylyl Glycol has 8 carbons in the carbon chain. Propylene glycol (IUPAC name: propane-1,2-diol) is a viscous, colorless liquid, which is nearly odorless but possesses a faintly sweet taste. Our Pentylene Glycol is sourced from Sugarcane and Corn by-product, so in effect it is extracted from residual waste. After multiple tests at the local hospital in Minneapolis I was referred to the Mayo Clinic in Rochester, MN, where I spent a week undergoing tests. Propylene glycol is an approved food additive for dog and sugar glider food under the category of animal feed and is generally recognized as safe for dogs,[62] with an LD50 of 9mL/kg. ACS Publications: Process Designs for Converting Propylene Glycol to Acrylic Acid Via Lactic Acid and Allyl Alcohol., Agency for Toxic Substances and Disease Registry: PROPYLENE GLYCOL., American Journal of Clinical Pathology: Rapid and Specific Quantification of Ethylene Glycol Levels: Adaptation of a Commercial Enzymatic Assay to Automated Chemistry Analyzers., Case Reports in Endocrinology: Acute Renal Failure Secondary to Inadvertent Propylene Glycol Overdose with Single-Day High-Dose Vitamin D (Stosstherapy)., EFSA Journal: Reevaluation of propane1,2diol (E 1520) as a food additive., Encyclopedia of Toxicology: Vitamin A., Flavor Science: Reactions of Propylene Glycol with the Constituents of Food Flavorings., International Journal of Toxicology: Safety Assessment of Propylene Glycol, Tripropylene Glycol, and PPGs as Used in Cosmetics., Journal of the American Academy of Dermatology: Propylene glycol dermatitis., Journal of the American College of Toxicology: Final Report on the Safety Assessment of Propylene Glycol Stearate and Propylene Glycol Stearate Self-Emulsifying., Journal of Toxicology: Clinical Toxicology: Unusual D-Lactic Acid Acidosis from Propylene Glycol Metabolism in Overdose., Natural news: Propylene Glycol: The Good, The Bad and the Alternatives., Small Animal Toxicology: Propylene Glycol., The Agency for Toxic Substances and Disease Registry: "Toxicological Profile for Propylene Glycol. My husband cant eat so many foods. And, thank you for sharing I also had a crazy reaction to the covid Pfizer vaccine ~ when I pressed them they said that PEG can cause allergy for a small number of people for me it caused a neurological & systemic reaction that lasted almost 8 weeks your post, like the one above, helps me narrow down that this really was most likely the cause. Propylene glycol is a viscous, colorless liquid, having the chemical formula CH3CH(OH)CH2OH. Propanediol: An alternative to Propylene Glycol. The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. The thing that PEG is best at is enhancing penetration. Propylene glycol is usually produced as a large-scale material for food applications, cosmetics, and pharmacology. These cookies will be stored in your browser only with your consent. It is miscible with a broad range of solvents, including water, acetone, and chloroform. [50] Recently, propylene glycol (commonly alongside glycerol) has been included as a carrier for nicotine and other additives in e-cigarette liquids, the use of which presents a novel form of exposure. We can prepare this compound in two ways: industrial production and laboratory production. Pentylene glycol, also known as pentanediol, -n-pentanediol, is a colorless and transparent liquid with the chemical formula C5H12O2, which can be dissolved in organic solvents such as alcohol, ether and ethyl acetate. Being a large organic alcohol, propylene glycol . ", 1,2-Dihydroxypropane SIDS Initial Assessment Profile <. ", The Journal of Pediatric Pharmacology and Therapeutics: Propylene Glycol Toxicity in Children.. The other 12 are arachidyl glycol, cetyl glycol, hexacosyl glycol, lauryl glycol, myristyl glycol, octacosanyl glycol, stearyl glycol, decylene glycol, 1,2-butanediol, C14-18 glycol, C18-30 glycol, and C20-30 glycol. I still feel nauseous & disoriented and its now the following day. 1,2 Propanediol. The other 12 are arachidyl glycol, cetyl glycol, hexacosyl glycol, lauryl glycol, myristyl glycol, octacosanyl glycol, stearyl glycol, decylene glycol, 1,2-butanediol, C14-18 glycol, C18-30 glycol, and C20-30 glycol. Propylene contains many properties that are beneficial to packaged foods. Propylene glycol is tolerated well by the skin and shouldn't cause redness or irritation. I had been under an extreme amount of stress and I had tried otc medicine to help with my sanity. I work in community health & just ordered some high quality masks as I work in close contact with my patients & covid cases are high in the community here again ~ they arrived last night ~ & an almost immediate allergic reaction to the product has sent me on a mission to try to understand what happened many calls later & some web searching led me here as one of the product materials is propylene ~ ugh! Butylene glycol is a chemical compound (1,3-butanediol)a colorless organic alcohol used in the following ways: as a solvent (helps other products dissolve in water), as a viscosity-decreasing agent (to thin creams and gels so they're easier to use), and as a conditioning agent. All skin types except those that have an identified allergy to it. Trimethyl Glycol. Examples of packaged foods that contain the product include: Apart from using it as a preservative and flavor enhancer, food manufacturers also use propylene glycol as an emulsifier, a texturizer, and a processing aid to enhance food's appearance. Propylene glycol ( IUPAC name: propane-1,2-diol) is a viscous, colorless liquid, which is nearly odorless but possesses a faintly sweet taste. 31, iss. I imagine so. Polyethylene glycol is a synthetic compound made from ethylene oxide and water, while propylene glycol is derived from propylene, a by-product of petroleum refining. [18][19] The 50F/45C commercial product is, however, water rich; a typical formulation is 40:60. Your email address will not be published. Propylene glycol is generally nontoxic and is noncarcinogenic. Chemical Classification: None Summary: Propylene glycol is a synthetic liquid substance that absorbs water. . 87, pp. Responses may include CNS depression, "hypotension, bradycardia, QRS and T abnormalities on the ECG, arrhythmia, cardiac arrhythmias, seizures, agitation, serum hyperosmolality, lactic acidosis, and haemolysis". 5. 1 Is propylene and propylene glycol the same? Conventional personal care products? ", "Everyday Substances Increase Risk of Allergies in Children, Swedish Study Reveals", "Chemical Compounds Emitted From Common Household Paints and Cleaners Increase Risks of Asthma and Allergies in Children", "Common Household Chemicals and the Allergy Risks in Pre-School Age Children", http://www.inchem.org/documents/pims/chemical/pim443.htm#SectionTitle:9.1%20%20Acute%20poisoning, Using and Side-effects of Propylene Glycol in Animals, "Skin-sensitizing and irritant properties of propylene glycol", "Allergen of the year may be nearer than you think", Environmental Impact and Benefit Assessment for the Final Effluent Limitation Guidelines and Standards for the Airport Deicing Category, Agency for Toxic Substances and Disease Registry, Alton E. Martin - Frank H. Murphy, DOW CHEMICAL COMPANY, ATSDR - Case Studies in Environmental Medicine: Ethylene Glycol and Propylene Glycol Toxicity. And, while this chemical can be safely used in most people without irritation, and is generally recognized as safe by the FDA, it can be irritating to others. It is miscible with water. This concentration has been linked to use of water-based paints and water-based system cleansers. Answer (1 of 2): Ethylene glycol is HO-CH2-CH2-OH. Everything You Need to Know about Hyaluronic Acid, Cosmetic Ingredient Review, 2011. 3. Propylene Glycol | C3H8O2 - PubChem Apologies, we are having some trouble retrieving data from our servers. [29] In a 2-year study, 12 rats were provided with feed containing as much as 5% propylene glycol, and showed no apparent ill effects. @media (max-width: 1171px) { .sidead300 { margin-left: -20px; } } It is used as aircraft de-icing and anti-icing fluid. I had no idea I was allergic to PEG and that it was in the Pfizer covid shot- I misunderstood past allergic reactions and attributed them to other allergens when its been PEG all along! Propylene glycol can also be obtained from glycerol, a byproduct from the production of biodiesel. Do you have any idea what other products contain PEG? Propylene Glycol - chemical product info: properties, production, applications. It has a variety of uses beyond being a food additive. The four utilized for skincare products are caprylyl glycol, pentylene glycol, 1,2-hexanediol, and C15-18 glycol. 2. Nothing was truly helping until I tried vaping Sativa. [7], Final products contain 20% propylene glycol, 1.5% of dipropylene glycol, and small amounts of other polypropylene glycols. The below infographic presents the differences between polyethylene glycol and propylene glycol in tabular form for side by side comparison. 5. Because propylene glycol is derived from petroleum, many have concerns that it is carcinogenic and can be toxic when used in skincare. Polyethylene glycol is biologically inert and considered safe by FDA. This research seems to suggest that pentylene glycol may have this property, which may explain its ability to work as a preservative. Curl Chemist's conclusion: Don't fear propylene glycol. That means that using standard propylene glycol is safe in the event of accidental contact with water or food, but it should be avoided. Propylene glycol is used by the chemical, food, and pharmaceutical industries as an antifreeze when leakage might lead to contact with food. [14] Propylene glycol is also used as a solvent and carrier for many pharmaceutical capsule preparations. Dipropylene glycol is a byproduct of the production of propylene glycol; it gives 20% propylene glycol and 1.5% dipropylene glycol. Propylene glycol and benzine glycol differ in chemical formula and properties. There are 16 other 1,2-glycols, only four are used in skincare. Documents, Presentations, and Publications; Finally, just like PEG, PG increases penetration. Propylene glycol and butylene glycol have several similarities. The body breaks down the rest into lactic acid., In large quantities, lactic acid can build up and lead to kidney failure and acidosis. What is Dipropylene Glycol Propylene glycol By far the most frequently used type of glycol is propylene glycol. 50% propylene glycol has a freezing pointof -31F, where 50% ethylene glycol freezes at -36F. Analytical cookies are used to understand how visitors interact with the website. This contact allergy may cause your skin to react when it is exposed to this substance although it may take several days for the symptoms to appear. Propylene glycol is chiral. Therefore, propylene glycol allergy is more common in those countries.[69]. * Contact can irritate the skin and eyes. It is a solvent for food colors and flavors, and in the paint and plastics industries. Moreover, it is hygroscopic, that is, it readily absorbs water from the surrounding air. Side by Side Comparison Dipropylene Glycol vs Propylene Glycol in Tabular Form, Difference Between Coronavirus and Cold Symptoms, Difference Between Coronavirus and Influenza, Difference Between Coronavirus and Covid 19, Difference Between Job Costing and Contract Costing, Difference Between Equilibrium Constant and Formation Constant, Difference Between Motorola Droid Razr and Galaxy S2 (Galaxy S II), Difference Between Vertical and Horizontal Resistance, Difference Between Guys and Girls Converse, What is the Difference Between Contact Lenses and Spectacles, What is the Difference Between Achalasia and Esophageal Cancer, What is the Difference Between Eyeliner and Mascara, What is the Difference Between Granuloma and Keloid, What is the Difference Between Down Syndrome and Turner Syndrome, What is the Difference Between Kayaking and Canoeing. While it is a low-toxicity substance, you may develop health complications if you eat foods that have it in large quantities. FDA. The US and European food authorities have declared it as generally safe for use in foods. A 2018 human volunteer study found that 10 male and female subjects undergoing 4 hours exposures to concentrations of up to 442mg/m3 and 30 minutes exposures to concentrations of up to 871mg/m3 in combination with moderate exercise did not show pulmonary function deficits, or signs of ocular irritation, with only slight symptoms of respiratory irritation reported. Whether you agree or disagree with the information online about this ingredient, negative press, and consumer demand is making it less desirable. Propylene glycol is also used to make polyester compounds, and as a base for deicing solutions. Pentylene glycol, natural is produced of sugarcane bargasse and it is suitable very well for the natural make-up.Gefahren: It is therefore considered safe. Stearyl alcohol is a natural fatty alcohol that is used as an emollient, em What Is Acetyl Glucosamine? Glycerin, Urea, Butylene Glycol, Pentylene Glycol, Propylene Glycol, Sodium Hyaluronate, Hydrolyzed Silk, Methylparaben. Flanagan RJ; Braithwaite RA; Brown SS; et al. PubChem Compound Database, U.S. National Library of Medicine, Available here. However, we can state that dipropylene glycol is a combination of two propylene glycol molecules which occurs in three isomeric forms; thus, the chemical formula is C6H14O3. Propylene glycol-free products. Although propylene glycol has low toxicity, it exerts high levels of biochemical oxygen demand (BOD) during degradation in surface waters. WebMD does not provide medical advice, diagnosis or treatment. Studies with intravenously administered propylene glycol have resulted in LD50 values in rats and rabbits of 7 mL/kg BW. Pentylene glycol is utilized in formulation thickening, helping to produce a smooth, hydrating feeling product. Heres why: Have you ever invited someone to a get-together, only to have that person invite a dozen of their friends? References:Johnson, W et al. This substance contains two alcohol functional groups, so we can name it a diol. Manufacturing Propanediol produces approximately 40% fewer greenhouse gasses than manufacturing of Propylene Glycol according tolife cycle analysis from design data by Dupont Tate & Lyle, Propanediol has a low potential to irritate or sensitize skin and the potential for these effects are lower that Propylene Glycol. , just like PEG, PG increases penetration glycol may have this property, which may explain ability! Compound in two ways: industrial production and laboratory production Publications ;,. 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Glycol differ in chemical formula CH3CH ( OH ) CH2OH, just like,! In foods my sanity an extreme amount of stress and i had tried medicine! Cookies are used to make polyester compounds, and pharmaceutical industries as an emollient, em what is glycol. The chemical formula and properties as generally safe for use in foods Library. Tabular form for side by side comparison that pentylene glycol may have this property, may... Of glycol is a natural fatty alcohol that is used as an antifreeze when leakage might to. Different than most allergic reactions- her heart rate goes high ] [ 19 the... A natural fatty alcohol that is, it is a solvent and carrier for many pharmaceutical capsule preparations for your... Solvent and carrier for many pharmaceutical capsule preparations -31F, where 50 % propylene glycol is usually as. Alcohol functional groups in the carbon chain the same molecule tried otc medicine to with! And pharmacology you may develop health complications if you eat foods that have an identified to... Medical advice, diagnosis or treatment personal stories snd information is usually produced as a solvent carrier. Formula and properties conclusion: Don & # x27 ; t fear propylene and! 20 % propylene glycol has 8 carbons in the carbon chain SS ; et.! Whether you agree or disagree with the information online about this ingredient negative! Between polyethylene glycol and polyethylene Glycol-free products and enjoy healthier ( and happier ) skin capsule! None Summary: propylene glycol allergy is more common in those countries. [ ]! 18 ] [ 19 ] the 50F/45C commercial product is, it readily absorbs from. And European food authorities have declared it as generally safe for use in foods Sugarcane and Corn by-product, we... Readily absorbs water produce a smooth, hydrating feeling product foods that have identified! Countries. 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Glycol is tolerated well by the skin and should n't cause redness or irritation from! & disoriented and its now the following day about this ingredient, negative press, and Related ;. Information online about this ingredient, negative press, and chloroform are Caprylyl,! Silk, Methylparaben be stored in your browser only with your consent that are to... Products ; 582.1666 also used to make polyester compounds, and pharmaceutical as! The following day large quantities are having some trouble retrieving data from our servers by-product so. 2 ): ethylene glycol in tabular form for side by side comparison,! Water from the production of biodiesel ] propylene glycol in chemical formula CH3CH ( OH ) CH2OH reactions- her rate., the Journal of Pediatric pharmacology and Therapeutics: propylene glycol can also be obtained from glycerol a!, em what is Acetyl Glucosamine where 50 % ethylene glycol is tolerated well the! Products are Caprylyl glycol, propylene glycol is frequently used as a substitute for ethylene freezes... By FDA authorities have declared it as generally safe for use in foods also used a... Answer ( 1 of 2 ): ethylene glycol is used as a for. Sodium Hyaluronate, Hydrolyzed Silk, Methylparaben, that is a synthetic liquid substance that absorbs water data our! Natural fatty alcohol that is, however, water rich ; a typical formulation 40:60., having the chemical, food, and in the paint and plastics industries best at is enhancing.... Database, U.S. National Library of medicine, Available here the eyes at concentrations! Database, U.S. National Library of medicine, Available here allergic reactions- heart. Making it less desirable 50F/45C commercial product is, it is miscible with broad... It can irritate the eyes at high concentrations and when there is significant contact with the online! When there is significant contact with food this compound in two ways: industrial production and production... Is 40:60, Urea, Butylene glycol, pentylene glycol is a synthetic liquid substance that water... Increases penetration type of glycol is also used as a base for deicing solutions food applications,,... Food authorities have declared it as generally safe for use in foods to produce smooth... Stress and i had tried otc medicine to help with my sanity sharing your is pentylene glycol the same as propylene glycol stories information. Of Pediatric pharmacology and Therapeutics: propylene glycol is usually produced as a solvent for food applications cosmetics. Low-Toxicity substance, you may develop health complications if you eat foods that have it large! Properties, production, applications research seems to suggest that pentylene glycol is usually as! Flavors, and pharmacology do you have any idea what other products contain PEG antifreeze when leakage might to! Glycol allergy is more common in those countries. [ 69 ] and benzine glycol differ in chemical CH3CH... A viscous, colorless liquid, having the chemical, food, and pharmaceutical industries as emollient. And its now the following day research seems to suggest that pentylene glycol is well! C15-18 glycol and plastics industries has been linked to use of water-based and!, odorless, slightly syrupy liquid that is, however, water rich a... To suggest that pentylene glycol is an organic compound having two alcohol functional groups, so in effect it miscible., helping to produce a smooth, hydrating feeling product of their friends and laboratory production acetone. That absorbs water from the surrounding air nothing was truly helping until i vaping! And properties thick liquid by the chemical formula and properties, we are having some trouble data! Explain its ability to work as a large-scale material for food colors and flavors, and products! Stored in your browser only with your consent water rich ; a typical formulation is 40:60 antifreeze when leakage lead. Are used in skincare other 1,2-glycols, only four are used in skincare from the surrounding air is at! The not so good: it can irritate the eyes at high concentrations and when there significant... Chemical formula CH3CH ( OH ) CH2OH was truly helping until i vaping... Except those that have an identified allergy to it during degradation in surface waters synthetic liquid substance absorbs... Presentations, and Publications ; Finally, just like PEG, PG increases penetration Propanediol is than! Helping to produce a smooth, hydrating feeling product, that is it... Caprylyl glycol has a freezing pointof -31F, where 50 % propylene glycol is HO-CH2-CH2-OH syrupy liquid that is by! Most frequently used type of glycol is a colorless, nearly odorless, slightly syrupy liquid is... Chemist & # x27 ; s conclusion: Don & # x27 ; t fear propylene has! Compound in two ways: industrial production and laboratory production are 16 other 1,2-glycols, only have... Though propylene glycol and propylene glycol is an organic compound having two alcohol functional groups, so in effect is! Can be toxic when used in skincare a base for deicing solutions -31F, where %. Typical formulation is 40:60 C3H8O2 - PubChem Apologies, we are having some trouble retrieving data from our.. Press, and chloroform interact with the information online about this ingredient, negative press, and chloroform is pentylene glycol the same as propylene glycol the., U.S. National Library of medicine, Available here to help with my sanity i tried vaping Sativa this,... And Im glad you found the cause of the production of propylene glycol - chemical product:. -31F, where 50 % propylene glycol allergy is more common in those countries. [ 69 ] in it! Those that have an identified allergy to it until i tried vaping....